Research
Ongoing Research Studies
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CATARACTS The Animal Health Trust in the UK has identified a gene responsible for most Aussie cataracts and will soon develop a screening test. They are now trying to determine the reason for the considerable variation in age of onset and progression of our hereditary cataracts and are seeking samples and data on affected dogs. ASHGI is coordinating sample submission in North America and Australia. HYPOTHYROIDISM AND OWNER-DIRECTED AGGRESSION This project’s goal is to establish whether thyroid replacement treatment is helpful in treating behaviour problems. They need dogs exhibiting owner-directed aggression and may provide testing if thyroid status is unknown. HYALOID ARTERIES This project seeks to determine if these are hereditary and why a few of them will be associated with cataracts. EPILEPSY Canine Epilepsy Network – The goal of this project is to develop a screening DNA test for the disease. EFFECTS OF MDR1 ON ANTI-SEIZURE MED EFFECTIVENESS The study’s goal is to determine whether the MDR1 mutation makes epileptic dogs less responsive to seizure control medications. Samples (cheek swabs and a blood sample) needed from purebred Australian Shepherds with epilepsy who are currently being treated with anti-seizure medications. NEURONAL CEROID LIPOFUSCINOSIS (NCL) NCL is a lethal neurological disease. Symptoms can include vision problems, loss of coordination, loss of training, personality changes (e.g. increased aggressiveness), movement problems (e.g. loss of ability to jump up onto an elevated surface or falling over), and seizures. They are interested in Aussies that are exhibiting any of these symptoms. CANINE BEHAVIOURAL GENETICS The study is currently focusing on problem behaviours with long-term goals of determining the genetic basis for a wide variety of canine behaviours. Understanding the genetics of these traits can aid breeders in the proper rearing, training and homing of puppies and dogs. They are collecting data via questionnaires and DNA cheek swabs. They would |